Search results for "health physics"

showing 6 items of 6 documents

Hadron therapy information sharing prototype

2013

The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and rep…

Health Physics and Radiation EffectsDatabases FactualComputer scienceHealth Toxicology and MutagenesisInformation Disseminationdata federationcancer informaticsweb portalSemanticscomputer.software_genreHealth informaticsPersonalizationAccess to Information03 medical and health sciences0302 clinical medicineSoftwareeHealthProton Therapyproton therapyRadiobiology and ClinicsHumansRadiology Nuclear Medicine and imaging030304 developmental biology0303 health sciencesRadiationManchester Cancer Research Centrebusiness.industryInformation DisseminationInformation sharingResearchInstitutes_Networks_Beacons/mcrcData scienceEurope030220 oncology & carcinogenesisInterdisciplinary CommunicationeHealthhadron therapybusinesscomputerAlgorithmsMedical InformaticsSoftwareData integration
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Production of mass-separated Erbium-169 towards the first preclinical in vitro investigations

2021

The β−-particle-emitting erbium-169 is a potential radionuclide toward therapy of metastasized cancer diseases. It can be produced in nuclear research reactors, irradiating isotopically-enriched 168Er2O3. This path, however, is not suitable for receptor-targeted radionuclide therapy, where high specific molar activities are required. In this study, an electromagnetic isotope separation technique was applied after neutron irradiation to boost the specific activity by separating 169Er from 168Er targets. The separation efficiency increased up to 0.5% using resonant laser ionization. A subsequent chemical purification process was developed as well as activity standardization of the radionuclid…

Medicine (General)Health Physics and Radiation Effectselectromagnetic isotope separationEr-169030218 nuclear medicine & medical imagingIsotope separationlaw.invention03 medical and health sciencesR5-9200302 clinical medicineErbium-169lawLASER RESONANCE IONIZATIONIonizationEr-169; activity standardization; electromagnetic isotope separation; in vitro studies; lanthanide-separation; laser resonance ionizationNeutron irradiationOriginal Researchin vitro studiesRadionuclideChemistryRadiochemistryGeneral MedicineLANTHANIDE-SEPARATIONIn vitroELECTROMAGNETIC ISOTOPE SEPARATIONER-169030220 oncology & carcinogenesisRadionuclide therapyMedicinelanthanide-separationactivity standardizationSpecific activitylaser resonance ionizationACTIVITY STANDARDIZATIONIN VITRO STUDIESFrontiers in Medicine
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Aging measurements with the gas electron multiplier (GEM)

2001

Abstract Continuing previous aging measurements with detectors based on the Gas Electron Multiplier (GEM), we investigated a 31×31 cm 2 triple-GEM detector, as used in the small area tracking of the COMPASS experiment at CERN. With a detector identical to those installed in the experiment, long-term high-rate exposures to 8.9 keV X-ray radiation were performed to study its aging properties. In standard operation conditions, with Ar/CO2 (70:30) gas filling and operated at an effective gain of 8.5×103, no change in gain and energy resolution is observed after collecting a total charge of 7 mC / mm 2 , corresponding to seven years of normal operation. This observation confirms previous results…

PhysicsNuclear and High Energy PhysicsHealth Physics and Radiation EffectsLarge Hadron Colliderbusiness.industryPhysics::Instrumentation and DetectorsPhysicsResolution (electron density)DetectorRadiationTracking (particle physics)Nuclear physicsOpticsGas electron multiplierCOMPASS experimentddc:530Detectors and Experimental TechniquesbusinessInstrumentation
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Practical recommendations for the application of DE 59/2013

2019

The changes introduced with Council Directive 2013/59/Euratom will require European Member States adapt their regulations, procedures and equipment to the new high standards of radiation safety. These new requirements will have an impact, in particular, on the radiology community (including medical physics experts) and on industry. Relevant changes include new definitions, a new dose limit for the eye lens, non-medical imaging exposures, procedures in asymptomatic individuals, the use and regular review of diagnostic reference levels (including interventional procedures), dosimetric information in imaging systems and its transfer to the examination report, new requirements on responsibiliti…

medicine.medical_specialtyPopulationRadiation Dosage030218 nuclear medicine & medical imaging03 medical and health sciencesDose limit0302 clinical medicineOccupational ExposureLens CrystallinemedicineHumansRadiology Nuclear Medicine and imagingMedical physicsEuropean UnionEye lenseducationBSSEuropean Directive EuratomRadiodiagnostic and radiotherapeutic proceduresMedical exposureRadiation protectioneducation.field_of_studymedicine.diagnostic_testbusiness.industryMember statesInterventional radiologyGeneral MedicineRadiation ExposureReference StandardsDirective030220 oncology & carcinogenesisRadiological weaponAccidentalAsymptomatic DiseasesEmergenciesSafetyRadiologybusinessHealth PhysicsLa radiologia medica
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Editorial from guest editors current Euratom legislation (DE 59/2013): new patient management in radiation protection.

2019

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medicine.medical_specialtySafety ManagementLegislationHealth PhysicRadiation ProtectionRadiation MonitoringmedicineHumansRadiology Nuclear Medicine and imagingMedical physicsEuropean UnionRadiation InjurieRadiation InjuriesNeuroradiologymedicine.diagnostic_testbusiness.industryRadiation doseRadiation doseInterventional radiologyGeneral MedicineRadiation ExposurePatient managementRadiation protectionCurrent (fluid)businessEuratom legislationHealth PhysicsHumanLa Radiologia medica
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FMECA Application in Tomotherapy: Comparison between Classic and Fuzzy Methodologies

2022

Accident analysis in radiotherapy highlighted the need to increase quality assurance (QA) programs by the identification of failures/errors with very low probability (rare event) but very severe consequences. In this field, a Failure Mode, Effects and Criticality Analysis (FMECA) technique, used in various industrial processes to rank critical events, has been met with much interest. The literature describes different FMECA methods; however, it is necessary to understand if these tools are incisive and effective in the healthcare sector. In this work, comparisons of FMECA methodologies in the risk assessment of patients undergoing treatments performed with helical tomotherapy are reported. …

risk assessment; FMEA; FMECA; radiotherapy; health physics; fuzzy risk priority numberRenewable Energy Sustainability and the Environmentfuzzy risk priority numberEcology Evolution Behavior and SystematicsFMEAradiotherapySettore ING-IND/19 - Impianti NucleariGeneral Environmental ScienceRisk assessmentFMECAhealth physics
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